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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1517 |
Benserazide hydrochloride
Benserazide HCl,盐酸苄丝肼,Serazide,Ro 4-4602 |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Benserazide hydrochloride (Ro 4-4602) 是一种芳香族 L-氨基酸脱羧酶(AADC)的抑制剂,常用于帕金森病。 | |||
T2148 |
Carbidopa monohydrate
Carbidopa Hydrate,S(-)-Carbidopa,卡比多巴水合物 |
Decarboxylase; Aryl Hydrocarbon Receptor | Immunology/Inflammation; Metabolism; Others |
Carbidopa monohydrate (S(-)-Carbidopa) 是一种外周型脱羧酶抑制剂,可用于帕金森病的研究。它是一种选择性芳香烃受体 (AhR) 调节剂。它抑制胰腺癌细胞和肿瘤生长。 | |||
T5954 |
Methyldopa hydrate
L-甲基多巴,Alpha-Methyldopa Sesquihydrate,L-(-)-α-Methyldopa hydrate,MK-351 hydrate,Methyldopa Sesquihydrate |
Dopamine Receptor; Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Methyldopa hydrate (MK-351 hydrate) 是一种前药,在中枢神经系统中被代谢成 α-Methylepinephrine。它是一种 α-肾上腺素能激动剂,对α2-adrenergic receptors 有选择性。 | |||
T15701 |
Methyldopa hydrochloride
L-(-)-α-Methyldopa hydrochloride,MK-351 hydrochloride |
Others | Others |
L-(-)-α-Methyldopa hydrochloride is an alpha-adrenergic agonist psychoactive drug. It is used as a sympatholytic or antihypertensive. Methyldopa has a dual mechanism of action. It is a competitive inhibitor of the enzyme DOPA decarboxylase, which converts | |||
T20396 |
Levadopa Related Compound A
6-Hydroxydopa, L-,L-Hydroxydopa |
||
Levadopa Related Compound A is the 6-hydroxy derivative of the amino acid L-DOPA with neurotoxic properties. Exogenously administered 6-Hydroxy-L-DOPA is biotransformed by an amino acid decarboxylase to the highly potent and catecholamine-selective neurot | |||
T1517L |
Benserazide
Ro-44602,Ro44602,Ro 44602,Serazide |
||
Benserazide is an inhibitor of dopa decarboxylase. It is often given with levodopa in the treatment of Parkinson's to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system an | |||
T36207 |
Methylspinazarin
|
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Methylspinazarin is a naphthoquinone bacterial metabolite that has been found in Streptomyces and is an inhibitor of catechol O-methyltransferase (COMT; IC50 = 0.8 μg/ml).1 It is selective for COMT over tyrosine hydroxylase, DOPA decarboxylase, and dopamine-β-hydroxylase at 100 μg/ml. Methylspinazarin decreases blood pressure in spontaneously hypertensive rats when administered at a dose of 50 mg/kg. |1. Chimura, H., Sawa, T., Takita, T., et al. Methylspinazarin and dihydromethylspinazarin, gate... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0848 |
L-DOPA
左旋多巴,Levodopa,3,4-Dihydroxyphenylalanine |
Dopamine Receptor; Endogenous Metabolite | GPCR/G Protein; Metabolism; Neuroscience |
L-DOPA (Levodopa) 是的神经递质多巴胺的代谢前体,具有口服活性。Levodopa 能够透过血脑屏障,并在大脑中转化为多巴胺。Levodopa 具有抗痛觉过敏作用。Levodopa 还具有帕金森氏病的研究潜力。 | |||
TN3607 | Catalpalactone | cAMP | GPCR/G Protein |
Catalpalactone exhibits high antitermitic, and cytotoxic activities, it exhibits potent inhibitory effects on lipopolysaccharide-induced NO synthesis in RAW 264.7 cells , with IC50 values of 9.80 microM. Catalpalactone can inhibit dopamine biosynthesis by |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02472 |
DOPA Decarboxylase/DDC Protein, Mouse, Recombinant (His)
Aadc,dopa decarboxylase (aromatic L-amino ... |
Mouse | Baculovirus Insect Cells |
DOPA Decarboxylase/DDC Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 55.2 kDa and the accession number is O88533. | |||
TMPY-01060 |
DOPA Decarboxylase/DDC Protein, Human, Recombinant (His)
dopa decarboxylase (aromatic L-amino acid ... |
Human | Baculovirus Insect Cells |
DOPA Decarboxylase/DDC Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 55 kDa and the accession number is Q53Y41. |